05 · Resources

Everything you need to bring MTAP into routine practice.

Materials below are intended for clinicians, pathologists, and laboratory staff. They are educational in nature and do not endorse any specific therapy or institution.

Reference card

MTAP testing quick reference

One-page summary of IHC, FISH, and NGS approaches with interpretation cutoffs.

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Reading list

Key MTAP & PRMT5 literature

Curated foundational papers on the synthetic lethal relationship and recent clinical updates.

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Case discussion

Molecular tumor board templates

Discussion prompts and reporting templates for surfacing MTAP findings in MTB.

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Patient handout

What MTAP means — for patients

Plain-language explainer to share with patients whose tumors carry MTAP loss.

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ClinicalTrials.gov

Search active and completed trials referencing MTAP status.

cBioPortal

Explore MTAP deletion frequencies across published genomic datasets.

CAP Molecular Pathology

Reference standards for molecular and copy-number testing in solid tumors.

BMS Clinical Trials

Investigator-sponsored and industry-sponsored trial directory.

Stay current

Sign up for MTAP educational updates.

New literature, evolving guidelines, and trial milestones — no promotional content.

Clinical trials

When testing reveals an MTAP deletion, a trial may be the next conversation.

Investigational PRMT5 inhibitors are being studied in patients whose tumors carry homozygous MTAP loss. Refer eligible patients early — site activation, screening, and consent take time.

Search the trial directory